Diagnosis of drug allergies

A new and highly effective method for diagnosing immediate hypersensitivity reactions, in particular drug allergies to systemic antibiotics, is the Basophil Activation Test (BAT). This in vitro cellular method for diagnosing allergies is based on assessing changes in the expression of markers of basophil activation and/or degranulation in response to allergen exposure using flow cytometry.

When assessing the clinical significance of the diagnosed allergen, VAT serves as the same functional test as a provocative test, but performing this study eliminates the potential risk to the patient.

Scientists at the Institute have developed a unique modification of the BAT, which allows for the most reliable diagnosis of IgE-mediated allergies, taking into account the immunofunctional properties of basophils. The use of a specific positive control to exclude the phenomenon of “non-responding” basophils provides high diagnostic efficiency in relation to allergies to antibacterial drugs from the beta-lactam and fluoroquinolone groups with sensitivity up to 70-77% and specificity up to 90%.

For additional information and to make an appointment with specialists, please call the following phone numbers:

+375 (17) 378 18 21
+375 (44) 574 18 21 (Viber, WhatsApp, Telegram)
e-mail: med@ibce.by