Human corneal limbus epithelial stem cells

This biomedical cell product (BMCP) is produced on the basis of autologous limbal epithelial stem cells (LESC) isolated from the patient’s keratolimbal flap and cultured until a therapeutic dose is received.

Transplantation of BMCP based on LESC is indicated for mechanical injuries, radiation and chemical burns of the cornea, recurrent corneal erosions, chronic keratitis, and keratitopathies of various origins (Stevens-Johnson syndrome, cicatricial pemphigoid, trachoma, congenital aniridia, etc.).

Local administration of cultured LESCs as part of complex cell therapy compensates for limbal insufficiency and ensures stable regeneration of the corneal epithelium, maintaining its regenerative properties for a long time, including for subsequent successful corneal transplantation.